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The approval introduces a new maintenance treatment option for patients with HR+/HER2+ advanced breast cancer, following a global academic collaboration that includes PrECOG.
PrECOG, LLC, collaborated with global partners on the first large, randomized phase 3 study to show a clinical benefit for CDK4/6 inhibition in HR+, HER2+ metastatic disease, resulting in a 15-month improvement in progression-free survival.
Clinical Cancer Research has published a report detailing the safety and efficacy of pelareorep combined with paclitaxel chemotherapy, with or without the checkpoint inhibitor avelumab, for patients whose disease progressed after first-line treatment.
Trial PrE0405 met its primary endpoint. Venetoclax combined with bendamustine+rituximab as the first therapy for MCL in patients over age 60 led to a complete response rate of 85%. The American Society of Hematology 2023 annual meeting featured the data.
Researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and PrECOG, LLC, will present six oral and three poster presentations at the 65th American Society of Hematology Meeting & Exposition, occurring in San Diego, California and virtually December 9 – 12, 2023.